New Grading System for the Evaluation of Chronic Ocular Manifestations in Patients with Stevens-Johnson Syndrome.
Tuesday, April 17, 2007 23:04 IST Sanghita Singh
NEW DELHI: There could be light at the end of the tunnel for those
suffering from eye ailments and awaiting eye transplants due to damaged corneas. Chennai-based microbiologist H N Madhavan of Sankara Netralaya, along with Japanese polymer scientist Prof Muri from the Vasada University of Tokyo, has devised a method to treat corneal damage that regenerates destroyed cells without the need fortransplants. With tests on rabbits completed successfully, the duo isnow waiting to carry out similar trials on human subjects.....
Department of Ophthalmology, University of California at Irvine, Irvine, California 94143, USA.
A 17-year-old boy presented with multiple, progressively enlarging cystic masses located at the junction of the lower eyelids and anterior orbit, 1 year after recovery from Stevens-Johnson syndrome. Bilaterally, symblepharon obliterated the inferior fornix and restricted supraduction. All but 1 cyst (which was sent for microscopic evaluation) was marsupialized. Cut edges of the cysts were sutured to adjacent conjunctiva and the epithelial walls were used as fornix lining. Histologically, the wall of the excised cyst consisted of conjunctiva. One year after surgery, the inferior fornices remained substantially deepened with improved ocular motility. This case demonstrated that conjunctival inclusion cysts occurring in the aftermath of Stevens-Johnson syndrome can be effectively managed with marsupialization. The epithelial lining can then be used in fornix reconstruction.
PMID: 17117107 [PubMed - in process]